The main results from the MeDD project have been published in a special issue from Biomedical Engineering. This special issue focuses on low liquid flows in medical technology, mainly with regard to drug delivery and infusion systems, click here to get access to the articles (subscription may be required). Download Special Issue editorial
Recently the project team has won a new grant! With this new grant the knowledge and experience gained on infusion technology will be made available through an e-learning module. We are very proud this course will be offered on the e-learning platform from the European Society of Intensive Care Medice (ESICM). Other close parthers are the European Society of [...]
This E-learning is intended to create awareness on the risks of multi-infusion. Our aim is to improve your understanding of the physical characteristics of infusion systems. We discuss both pumps and disposables. We focus on their influence on the dose rate and potential dosing errors that can be clinically relevant.
In this report it is studied whether typical infusion pumps perform within accuracy specifications. Additionally, the startup time is studied. This is a very important parameter because it defines how long it takes before the patient receives the infusion doses that it needs. It will also be investigated how the compliance and start up delay depend [...]
In task 1.4.2 the primary standards are subject to an inter comparison by means of a flow meter and a flow generator. This report covers the part of the characterization of the flow generator, in this case a syringe pump NEXUS 3000.
An intercomparison has been organized with the purpose to determine the degree of equivalence of several newly developed primary standards for liquid flow rates from 3 mg/h up to 200 mg/h (equivalent with 50 nl/min to 3.3 μl/min). This intercomparison is complementary to EURAMET project 1291/ EURAMET.M.FF.S7 to cover even lower flow rates (project 1291 [...]
Depency on several physical parameters, Reynolds number interpolation, and uncertainty estimation The aim of this report is to determine the influence of various physical parameters and operating conditions on the performance of various types of flow meters. These parameters have been selected that are most relevant for drug delivery applications: viscosity, temperature, back pressure and pulsatile [...]
This best practice guide concerns various aspects related to infusion technology and is developed for clinical users such as nurses and physicians. This guide is put together based on a literature research and on lessons learned from MeDD and focuses on critical drug delivery applications. Here, critical is defined as those applications that require an [...]
MeDD organized a 1-day symposium on infusion technology May 22. This symposium aimed at bringing together researchers, doctors, nurses and clinical physicist in the field of drug delivery. More than 80 people attended from 11 different countries. Below you will find the program and presentations. Session 1 Results MeDD (1) Overview metrology for drug delivery (VSL, [...]
Patients on the Intensive Care Unit almost always require infusion therapy. The continuous and stable infusion of drugs is necessary to stabilize and treat the patient. To predict the infused drug concentration, the UMC has developed a simulation model which is discussed in this technical report.