The UMC Utrecht has developed an in-vitro measurement method to measure concentrations in infusion lines of multi-infusion while simulating several manual disturbances in one or more pumps. This method relies on spectrophotometry and flow meters. The spectrophotometry is used to determine the concentration of added dies whereas the flow meters measure the flow rate of the individual lines. The aim of this report is to provide a literature overview of studies describing similar multi-infusion concentration measurement and flowmetry methods.
