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Multi infusion E-learning

This E-learning is intended to create awareness on the risks of multi-infusion. Our aim is to improve your understanding of the physical characteristics of infusion systems. We discuss both pumps and disposables. We focus on their influence on the dose rate and potential dosing errors that can be clinically relevant.

2017-10-24T08:01:07+00:00June 11th, 2015|

Assessment of drug delivery devices and accessories

In this report it is studied whether typical infusion pumps perform within accuracy specifications. Additionally, the startup time is studied. This is a very important parameter because it defines how long it takes before the patient receives the infusion doses that it needs. It will also be investigated how the compliance and start up delay depend [...]

2016-09-12T14:27:49+00:00June 1st, 2015|

Characterisation of hte flow generator NEXUS 3000

In task 1.4.2 the primary standards are subject to an inter comparison by means of a flow meter and a flow generator. This report covers the part of the characterization of the flow generator, in this case a syringe pump NEXUS 3000.

2016-09-12T14:28:24+00:00May 20th, 2015|

Comparison of primary standards for liquid nano flow rates

An intercomparison has been organized with the purpose to determine the degree of equivalence of several newly developed primary standards for liquid flow rates from 3 mg/h up to 200 mg/h (equivalent with 50 nl/min to 3.3 μl/min). This intercomparison is complementary to EURAMET project 1291/ EURAMET.M.FF.S7 to cover even lower flow rates (project 1291 [...]

2016-09-12T14:30:07+00:00May 19th, 2015|

Flow meter assessment

Depency on several physical parameters, Reynolds number interpolation, and uncertainty estimation The aim of this report is to determine the influence of various physical parameters and operating conditions on the performance of various types of flow meters. These parameters have been selected that are most relevant for drug delivery applications: viscosity, temperature, back pressure and pulsatile [...]

2016-09-12T14:29:10+00:00May 19th, 2015|

Best practice guide

This best practice guide concerns various aspects related to infusion technology and is developed for clinical users such as nurses and physicians. This guide is put together based on a literature research and on lessons learned from MeDD and focuses on critical drug delivery applications. Here, critical is defined as those applications that require an [...]

2016-09-12T14:25:30+00:00May 19th, 2015|

Presentations 1-day symposium on infusion technology

MeDD organized a 1-day symposium on infusion technology May 22. This symposium aimed at bringing together researchers, doctors, nurses and clinical physicist in the field of drug delivery. More than 80 people attended from 11 different countries. Below you will find the program and presentations. Session 1 Results MeDD (1) Overview metrology for drug delivery (VSL, [...]

2016-09-12T14:24:38+00:00May 10th, 2015|

A theoretical model for catheter outflow

Patients on the Intensive Care Unit almost always require infusion therapy. The continuous and stable infusion of drugs is necessary to stabilize and treat the patient. To predict the infused drug concentration, the UMC has developed a simulation model which is discussed in this technical report.

2016-09-12T14:33:22+00:00February 3rd, 2015|

Measurement methods in multi-infusion: a literature review

The UMC Utrecht has developed an in-vitro measurement method to measure concentrations in infusion lines of multi-infusion while simulating several manual disturbances in one or more pumps. This method relies on spectrophotometry and flow meters. The spectrophotometry is used to determine the concentration of added dies whereas the flow meters measure the flow rate of [...]

2016-09-12T14:33:54+00:00February 3rd, 2015|

Results survey of medication protocols

Medication protocols allow clinicians to administer the correct amount of medication to the patient. Medication protocols may include any procedure necessary to accomplish this goal safely, i.e. to prevent medical/medication errors. In cooperation with the JRP partners, the UMC Utrecht has compiled and disseminated a survey about medication protocols amongst European hospitals. The aim was [...]

2016-09-12T14:31:21+00:00February 3rd, 2015|
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